N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide and Disease-Models--Animal

N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide has been researched along with Disease-Models--Animal* in 1 studies

Other Studies

1 other study(ies) available for N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide and Disease-Models--Animal

Article	Year
Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity. Bioorganic & medicinal chemistry letters, 2008, Aug-01, Volume: 18, Issue:15 The biphenyl amides (BPAs) are a novel series of p38alpha MAP kinase inhibitor. The optimisation of the series to give compounds that are potent in an in vivo disease model is discussed. SAR is presented and rationalised with reference to the crystallographic binding mode. Topics: Administration, Oral; Animals; Benzamides; Biphenyl Compounds; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Disease Models, Animal; Mitogen-Activated Protein Kinase 14; Molecular Conformation; Molecular Structure; Protein Kinase Inhibitors; Rats	2008

Article

Year

Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity.

Bioorganic & medicinal chemistry letters, 2008, Aug-01, Volume: 18, Issue:15

The biphenyl amides (BPAs) are a novel series of p38alpha MAP kinase inhibitor. The optimisation of the series to give compounds that are potent in an in vivo disease model is discussed. SAR is presented and rationalised with reference to the crystallographic binding mode.

Topics: Administration, Oral; Animals; Benzamides; Biphenyl Compounds; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Disease Models, Animal; Mitogen-Activated Protein Kinase 14; Molecular Conformation; Molecular Structure; Protein Kinase Inhibitors; Rats

2008